Number Needed to Treat for Recurrent Events

Number Needed to Treat

Number needed to treat (NNT); number needed to harm (NNH).

Number needed to treat and baseline risks.

Deriving number-needed-to-treat and number-needed-to-harm from the SAINT I trial results.

Deriving Number-Needed-to-Treat and Number-Needed-to-Harm From the Saint I Trial Results To the Editor: In their recent publication regarding interpretation of the Stroke-Acute Ischemic NXY Treatment (SAINT I) trial,1 Koziol and Feng use the definition, but not the derivation method, for number-needed-to-treat (NNT) and number-needed-to-harm (NNH) that was previously described.2 As a result the...

Number needed to treat: enigmatic results for exacerbations in COPD.

The number needed to treat (NNT), a simple tool to quantify the effectiveness or harm of a treatment, has been used in several studies of treatment for chronic obstructive pulmonary disease (COPD) [1, 2]. It provides the number of patients that need to be treated with the study drug for a given period of time, relative to the comparator, to prevent one patient from having the outcome event, e.g...